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United States Patent | 6,214,540 |
DeVico ,   et al. | April 10, 2001 |
The present invention relates to therapeutic compositions and methods for treating and preventing infection by an immunodeficiency virus, particularly HIV infection, using chemokine proteins, nucleic acids and/or derivatives or analogues thereof.
Inventors: | DeVico; Anthony L. (Alexandria, VA); Gallo; Robert C. (Bethesda, MD); Garzino-Demo; Alfredo (Washington, DC) |
Assignee: | University of Maryland Biotechnology Institute (Baltimore, MD) |
Appl. No.: | 826133 |
Filed: | March 26, 1997 |
Current U.S. Class: | 435/5; 424/85.1; 424/85.2; 424/185.1; 424/192.1; 424/195.11; 435/7.2; 435/7.24; 514/44; 530/351; 530/395; 536/23.4; 536/23.5 |
Intern'l Class: | C12Q 001/70; A61K 045/00; A01N 043/04; C07K 001/00 |
Field of Search: | 424/85.1,85.2,185.1,192.1,195.11 435/5,7.2,7.24 514/44 530/351,395 536/23.4,23.5 |
5141867 | Aug., 1992 | Ivanoff et al. | 435/252. |
Foreign Patent Documents | |||
WO 90/07119 | Jun., 1990 | WO. | |
WO 91/09872 | Jul., 1991 | WO. | |
WO 92/22654 | Dec., 1992 | WO. | |
WO 93/03735 | Mar., 1993 | WO. |
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