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United States Patent | 5,681,586 |
Gordon | October 28, 1997 |
A pharmaceutical composition comprising an improved modified protein sol is used for treating and enhancing the healing of arthritis and cutaneous acne. Prior to being modified, a protein is solubilized and neutralized by an alkali solution containing a molar weight percent ratio of 95:5 KOH/NaOH. Neutralization is allowed to continue for about 5 minute, allowing for complete neutralization of the protein. The neutralized protein is then hydrolyzed by enzymatic digestion. The improved modified protein sol may be then mixed with stabilizing and preserving agents, such as polyvinyl pyrrolidone, if desired. Uses for the improved modified protein composition includes treatment of arthritis and cystic acne.
Inventors: | Gordon; Arthur L. (109 Phaeton Dr., Wheeling, IL 60090) |
Appl. No.: | 660082 |
Filed: | June 3, 1996 |
Current U.S. Class: | 424/535; 424/78.06; 424/757; 424/DIG.13; 435/68.1; 514/2; 514/21; 530/360; 530/361; 530/832; 530/833 |
Intern'l Class: | A61K 035/20 |
Field of Search: | 514/2,21 424/80,DIG. 13,535,195.1 530/360,361,832,833 |
3558770 | Jan., 1971 | Gordon | 424/535. |
4883659 | Nov., 1989 | Goodman et al. | 424/78. |
4971800 | Nov., 1990 | Chess et al. | 424/449. |
5051260 | Sep., 1991 | Chess et al. | 424/449. |