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United States Patent | 5,609,744 |
Zenharusern ,   et al. | * March 11, 1997 |
An assembly suitable for identifying a code sequence of at least a portion of a biomolecule in a gel embodiment. The assembly comprises first means for migrating and separating a portion of a biomolecule in a gel; second means comprising a near-field probe for generating a super-resolution chemical analysis of a portion of a biomolecule; and, third means for correlating the super-resolution chemical analysis of the portion of the biomolecule with a broad spectral content of a referent biomolecule, for generating a code sequencing of the portion of the biomolecule.
Inventors: | Zenharusern; Frederic (Mohegan Lake, NY); Wickramasinghe; Hemantha K. (Chappaqua, NY) |
Assignee: | International Business Machines Corporation (Armonk, NY) |
[*] Notice: | The portion of the term of this patent subsequent to March 16, 2012 has been disclaimed. |
Appl. No.: | 405481 |
Filed: | March 16, 1995 |
Current U.S. Class: | 204/606; 204/616; 356/301; 356/318; 422/82.01; 422/82.08; 435/287.1; 435/287.2 |
Intern'l Class: | B01D 061/42; C12M 003/00 |
Field of Search: | 422/50,63,65,82.01,82.05,82.08,82.12 435/286.2,287.1,287.2,287.3 204/182.8,606,616 250/458.1,459.1,461.1,461.2,216 356/301,317,318 935/77,80 |
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