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United States Patent | 5,576,316 |
Cohn | November 19, 1996 |
A method for inhibiting tumor growth rate using creatine or creatine analogs is described. The creatine or creatine analogs are administered to subjects such that tumor growth rate is inhibited. Pharmaceutical compositions containing the creatine or creatine analogs and packaged products also are described.
Inventors: | Cohn; Mildred (Narberth, PA) |
Assignee: | University of Pennsylvania (Philadelphia, PA) |
Appl. No.: | 416499 |
Filed: | April 4, 1995 |
Current U.S. Class: | 514/218; 514/275; 514/385; 514/386; 514/396; 514/553; 514/561; 514/563; 514/564; 514/579; 514/631; 514/638; 514/646 |
Intern'l Class: | A61K 031/415; A61K 031/505; A01N 043/54; A01N 043/58 |
Field of Search: | 514/218,275,385,386,396,553,561,563,564,579,631,638,646 |
5219846 | Jun., 1993 | Bru et al. | 514/118. |
5324731 | Jun., 1994 | Kaddurah-Daouk et al. | 514/275. |